Is the "Ozempic Workout" Really a Thing? What You (and Your Muscles) Should Know
- Ashley Marie
- 10 minutes ago
- 3 min read
GLP-1 medications like Ozempic, Wegovy, and Mounjaro have revolutionized weight loss treatment. However, shedding pounds quickly comes with a hidden cost: muscle loss—and if you’re not pairing these medications with the right kind of movement, you could be trading one health risk for another.
For women in their 30s, 40s, and 50s—especially those navigating perimenopause or menopause—the risks are even more amplified. Without regular strength training, GLP-1 users may experience dramatic declines that aren't seen on the scale or when trying on clothes.
It’s not just about slimming down; it’s about staying strong, mobile, and metabolically healthy during a period of life when your body is already working against you.

Why Muscle Loss Happens on GLP-1s
GLP-1 receptor agonists work by slowing digestion, curbing appetite, and altering hunger-related brain chemistry. While this leads to significant fat loss, it can also lead to substantial lean mass loss, especially if users aren't doing anything to preserve it.
Some studies suggest as much as 25-30% of weight lost on GLP-1s comes from muscle, not fat. That has serious implications for metabolism, strength, and long-term health.
This issue is even more pronounced for women in perimenopause and menopause. As estrogen levels decline, women naturally lose muscle mass and experience a slower metabolism.
Add in the appetite suppression from GLP-1s, and the risk of accelerated muscle loss becomes even higher. That’s why a proactive approach to fitness is not just recommended—it’s essential. Yes, even if you're experiencing the dreaded GLP-1 side effects.
Why Exercise Matters More Than Ever for Strong Muscles
If you're taking a GLP-1 and not working out, you're not just losing weight—you're potentially losing muscle, bone density, and functional strength. That matters more than just your scale weight.
Muscle helps regulate blood sugar, supports joints, and plays a key role in resting metabolic rate. Losing too much of it can slow metabolism and make it harder to maintain weight loss in the long term.
For women over 30, especially those navigating hormonal shifts, preserving muscle is critical for energy, mobility, and weight management. Strength training and resistance-based workouts can significantly offset muscle loss. It signals your body to retain lean mass even as you drop fat.
Cardiovascular exercises are still important for heart health, but on GLP-1s, strength training becomes non-negotiable.
What Is the Ozempic Workout?
Search "Ozempic workout" on social media or Google, and you'll see a flood of trainers and programs promising to help people on GLP-1s get fit fast.
But here's the truth: there’s no special workout exclusive to these meds—what’s really happening is a long-overdue focus on smart strength training and intentional fitness for people experiencing rapid weight loss, especially women facing hormonal shifts.
The term "Ozempic workout" has become shorthand for what these programs are actually addressing: the need to preserve muscle, protect metabolism, and build strength while on medication that suppresses appetite.
It’s not about trendy moves or gimmicky routines—it’s about helping your body adapt and stay strong while fat is coming off quickly.
These workouts prioritize:
Progressive resistance training: Meeting your body where it is and gradually building strength to prevent injury and combat muscle loss.
Protein and recovery education: Because muscle doesn’t build itself, especially during caloric deficits or hormonal changes.
Balance and core stability: Crucial for women in midlife whose coordination and joint health may already be changing.
Customized pacing: Recognizing that energy and appetite fluctuate while on GLP-1s, so programming must adapt accordingly.
This is more than a trend. In fact, it's what Legg Day Fitness has been doing from the start. Our programs give guidance that understands the intersection of healthy eating, workouts, and the unique physiology of women 30–55.

What Is the Legg Day Method?
The Legg Day Method offers programs rooted in functional strength, hormone-aware training, and real-world results. Plus, you get nutrition guidance and wellness workouts for your mind and soul.
Where we break apart from the pack is with accountability, tailored plans, and customized results based on your goals and best practices. We don't try to change your lifestyle; we try to improve your life.
For example, we don't like the word "diet" or "weight loss" around here too much. Words like that feel restrictive, temporary, and arbitrary. Instead, the Legg Day Method is about wellness wrapped in balance. No foods are off-limits. Our workouts keep you on a fit path without wasting time or setting unrealistic time goals in your busy life.
The Legg Day Method works differently for everyone. So, if you want an Ozempic workout or a GLP-1 meal plan, we can do that. However, it's not coming from a newly discovered magical place. It's just tailored to your preferences and bodily needs.
The shift is your mindset as we work together to craft an achievable balance of wellness, nutrition, and fitness.
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